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Raymond S Douglas Selected Research

teprotumumab

1/2022Teprotumumab for thyroid eye disease: early response is not required for benefit.
1/2022Proptosis and Diplopia Response With Teprotumumab and Placebo vs the Recommended Treatment Regimen With Intravenous Methylprednisolone in Moderate to Severe Thyroid Eye Disease: A Meta-analysis and Matching-Adjusted Indirect Comparison.
1/2022Expert Consensus on the Use of Teprotumumab for the Management of Thyroid Eye Disease Using a Modified-Delphi Approach.
1/2022Teprotumumab Efficacy, Safety, and Durability in Longer-Duration Thyroid Eye Disease and Re-treatment: OPTIC-X Study.
1/2022Teprotumumab for the treatment of chronic thyroid eye disease.
12/2021Teprotumumab in Clinical Practice: Recommendations and Considerations From the OPTIC Trial Investigators.
9/2021Facial and Eyelid Changes in Thyroid Eye Disease Are Reversed by Teprotumumab.
3/2021Thyroid eye disease: Redefining its management-A review.
1/2021Teprotumumab for non-inflammatory thyroid eye disease (TED): evidence for increased IGF-1R expression.
1/2021Teprotumumab for patients with active thyroid eye disease: a pooled data analysis, subgroup analyses, and off-treatment follow-up results from two randomised, double-masked, placebo-controlled, multicentre trials.
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Raymond S Douglas Research Topics

Disease

40Graves Ophthalmopathy
01/2022 - 09/2007
19Graves Disease (Basedow Disease)
09/2014 - 04/2006
16Exophthalmos (Proptosis)
01/2022 - 01/2010
8Diplopia (Double Vision)
01/2022 - 01/2019
7Inflammation (Inflammations)
01/2022 - 09/2007
5Optic Nerve Diseases (Optic Neuropathy)
01/2022 - 01/2011
5Hyperthyroidism
06/2012 - 10/2008
4Autoimmune Diseases (Autoimmune Disease)
11/2012 - 04/2006
3Body Weight (Weight, Body)
09/2021 - 01/2020
3Lagophthalmos
07/2018 - 01/2009
2Disease Progression
01/2021 - 06/2012
2Dry Eye Syndromes (Dry Eye Syndrome)
07/2018 - 01/2011
2Fibrosis (Cirrhosis)
01/2012 - 09/2011
2Wounds and Injuries (Trauma)
05/2009 - 11/2006
2Lacrimal Duct Obstruction
03/2008 - 03/2008
1Strabismus (Squint)
01/2022
1Paresthesia (Dysesthesia)
12/2021
1Hashimoto's encephalitis
01/2021
1Confusion (Bewilderment)
01/2021
1Hearing Loss (Hearing Impairment)
01/2021
1Spasm (Spasms)
01/2021
1Cicatrix (Scar)
07/2018
1Blepharospasm
07/2018
1Hyperglycemia
01/2017
1Pupil Disorders (Marcus Gunn Pupil)
09/2015
1Dermoid Cyst (Dermoid)
03/2010
1Neoplasms (Cancer)
03/2010
1Ectropion
07/2009
1Cataract (Cataracts)
01/2009
1Fistula
03/2008
1Sinusitis
03/2008
1Pain (Aches)
03/2008
1Enophthalmos
12/2006

Drug/Important Bio-Agent (IBA)

17Troleandomycin (TAO)FDA Link
01/2016 - 09/2008
16teprotumumabIBA
01/2022 - 01/2017
10Thyrotropin Receptors (Thyrotropin Receptor)IBA
01/2016 - 09/2008
4Insulin (Novolin)FDA Link
01/2019 - 03/2007
4CytokinesIBA
01/2016 - 07/2006
4IGF Type 1 Receptor (IGF 1 Receptor)IBA
01/2012 - 09/2008
3Rituximab (Mabthera)FDA Link
07/2014 - 01/2010
3Hyaluronic Acid (Hyaluronan)IBA
06/2014 - 01/2009
3AutoantigensIBA
06/2014 - 01/2010
3Interleukin-6 (Interleukin 6)IBA
11/2012 - 05/2009
3AntibodiesIBA
06/2012 - 01/2010
3AntigensIBA
09/2011 - 09/2008
2Insulin-Like PeptidesIBA
01/2021 - 09/2008
2CD40 Ligand (CD40L)IBA
12/2016 - 11/2012
2Thyrotropin (Thyroid-Stimulating Hormone)FDA Link
12/2016 - 09/2008
2AutoantibodiesIBA
06/2014 - 05/2012
2Interleukin-8 (Interleukin 8)IBA
01/2014 - 05/2009
2Adrenal Cortex Hormones (Corticosteroids)IBA
01/2010 - 09/2007
1MethylprednisoloneFDA LinkGeneric
01/2022
1Tricyclic Antidepressive Agents (Tricyclic Antidepressants)IBA
12/2021
1SteroidsIBA
09/2021
1GlucocorticoidsIBA
01/2019
1Botulinum Toxins (Botulinum Toxin)IBA
07/2018
1Lubricant Eye Drops (Artificial Tears)IBA
07/2018
1Fluorouracil (Carac)FDA LinkGeneric
07/2018
1Fibrin Tissue Adhesive (Fibrin Sealant)IBA
07/2018
1Pharmaceutical PreparationsIBA
01/2017
1Interleukin-12 (IL 12)IBA
12/2016
1LigandsIBA
11/2012
1ChemokinesIBA
05/2012
1Thyroid-Stimulating ImmunoglobulinsIBA
09/2011
1Complementary DNA (cDNA)IBA
09/2011
1SeleniumIBA
08/2011
1Antithyroid Agents (Antithyroid Drugs)IBA
01/2011
1Dinoprostone (PGE2)FDA Link
12/2010
1RestylaneIBA
07/2009
1SeprafilmIBA
05/2009
1GoldIBA
01/2009
1gadolinium-IGG complexIBA
09/2008
1Biological ProductsIBA
09/2008
1vinyl polysiloxane (polyvinyl siloxane)IBA
03/2008
1HydrogelsIBA
03/2008
1SiliconesIBA
03/2008
1Polymethyl Methacrylate (Sol)IBA
11/2006
1Interleukin-4 (Interleukin 4)IBA
07/2006
1Interleukin-16 (Interleukin 16)IBA
04/2006
1Chemokine CCL5IBA
04/2006
1Immunoglobulin G (IgG)IBA
04/2006

Therapy/Procedure

11Therapeutics
01/2022 - 09/2008
4Decompression
01/2019 - 09/2015
2Intravenous Infusions
01/2021 - 01/2020
2Immunotherapy
06/2012 - 09/2011
2Dacryocystorhinostomy
03/2008 - 03/2008
1Tissue Expansion
09/2021
1Retreatment
01/2021
1Meridians (Jing Luo)
11/2017
1Ligation
11/2012
1Surgical Decompression
06/2012
1Drug Therapy (Chemotherapy)
08/2011
1Biological Therapy
01/2011
1Sutures (Suture)
03/2010
1Slit Lamp
07/2009
1Oral Surgery (Maxillofacial Surgery)
03/2008
1Stents
03/2008
1Prostheses and Implants (Prosthesis)
12/2006